Setting up document management in SharePoint involves configuring libraries, metadata, permissions, and workflows to streamline document storage, collaboration, and retrieval. Start by creating a document library, setting up metadata and content types for categorization, defining permissions and access controls, enabling versioning for tracking changes, and implementing workflows for approvals and automation. Utilize retention policies and search features to manage document lifecycle and ensure compliance. SharePoint’s integration with Microsoft 365 tools enhances productivity, making it a powerful document management system for organizations.